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Labsr4U Pawsitive Advice
Allergies
The following article was written by Rachel Peeples, DVM
The term allergies is a general term for a variety of conditions in
which the immune system "overreacts" to foreign material that is not
harmful to the body. The immune system's job is to protect the animal
from harmful material be it toxins, bacteria, viruses, etc. It does this
by recognizing foreign substances, or antigens, and producing protective
proteins, or antibodies, to them. The antibodies bind to the antigens
and stimulate the body's immune cells to destroy the antigen.
During this process, chemicals are released that make the blood vessels
in the area of the antigen become leaky producing swelling, that
increase blood flow to the area producing heat and redness, that
initiate itchy and pain sensations, and that sometime cause systemic
signs like fever and shortness of breath. Normally, these are all
defense mechanisms that serve to remove the dangerous foreign material
from the body and keep the animal healthy.
Sometimes, however, the immune system reacts to substances that are
foreign but are not harmful. These substances are called allergens.
Animals can be allergic to absolutely anything just as people can. And
what they are allergic to and how allergic they are is highly
individual. There is some evidence that allergies are partially the
result of minor abnormalities in the immune system that are genetically
linked. So, breeding a strongly allergic dog or bitch is not
recommended.
The most common allergies in dogs are flea allergies, atopy (or inhalant
allergies), and food allergies. Less common are contact allergies.
Flea allergy is just what its name implies -- an allergy to fleas. The
classic presentation of a flea allergy is a VERY, VERY itchy dog that
has hair loss in a V-shape along the back at the base of the tail, along
the stomach, and along the back of the back legs. These areas of hair
loss also have reddened skin that can become darker (hyperpigmented) and
thickened (lichenification). Often scratches and other lesions occur as
a result of the scratching and biting to relieve the itchiness, and
secondary bacterial infections are quite common. Diagnosis is based on
the presence of fleas (it takes only one in very allergic dogs), the
distribution of the lesions, and rarely on actual skin allergy tests.
The treatment that is most effective is keeping the dog and its
environment flea free. That is much easier today than in previous times
due to the monthly flea products like Advantage and Top-Spot. As word of
caution -- Program is an excellent flea control product BUT is requires
that the flea bite the dog to be affected. Program alone is not going to
work for the flea allergic dog. Program in combination with adult flea
control products is a very powerful and effective combination.
Atopy is another common allergic condition. It is an allergic reaction
to inhalant allergens like pollen, dust, dried up insect parts, animal
dander (yes your dog can be allergic to your cat :-)!!), molds, etc. The
common presentation of atopy is an itchy dog that constantly scratches
or licks its feet, face, and ears. Often these dogs will drag their
muzzles across the carpet. Dogs with atopy often have a history of
recurrent ear infections and skin infections. Mild atopy can present as
merely mild itching and slightly reddened skin. Severe atopy can present
as intense itchiness, hair loss especially on the face and feet, red
staining on the feet from licking, hyperpigmented and lichenified skin,
and often secondary bacterial infections from the trauma of scratching.
Typically, atopy is seasonal, that is, it is worse in the spring or
fall. But sometimes atopy can be year-round especially for allergies to
house dust and animal dander. Diagnosis is based on the signs, the
history of being seasonal and VERY responsive to antihistamines (benadryl)
and steroids (prednisone), and a positive allergy skin test for airborne
allergens. Treatment consists ideally of allergy "shots" to desensitize
the animal, antihistamines, regular baths, and only occasionally
steroids. Average age of onset is one to two years and the condition
tends to worsen as the animal ages if untreated.
Food allergies are one of the more frustrating allergies to deal with
for it is often a diagnosis of exclusion. That is, it is diagnosed after
flea allergies and atopy have been ruled out. Food allergies occur when
the immune system reacts to a substance (usually a protein) in the diet.
Signs can mimic any of the allergies -- with hair loss, red skin, thick
skin, etc anywhere. Often the feet and ears are the two areas most
affected but that is highly variable. The dog is itchy though not as
much as with flea allergies or atopy, and the itchiness responds poorly
to antihistamine or steroid treatment. Often food allergic dogs have a
history of year-round itchiness and recurrent ear infections. Diagnosis
is often made by ruling out flea allergies and atopy in itchy dogs. Food
trials are the definitive means of diagnosing food allergies. In a food
trial the dog is fed a hypoallergenic diet that has one protein and one
carbohydrate source. Common hypoallergenic diets are rabbit and potato,
fish and rice, venison and potato, and more recently kangaroo and
potato. Let me take a moment to comment here about lamb and rice diets.
Initially, in the United States lamb and rice was the hypoallergenic
diet simply because there was very little lamb dog foods available at
the time. For some reason, the dog world has gotten the idea that lamb
and rice is a better diet than the others for all dogs. This is simply
not true especially since most lamb and rice diets today are lamb and
rice and a bunch of other stuff (read your labels). So, do not assume
that just because you feed a lamb and rice diet that the diet is
hypoallergenic or will prevent food allergies from developing. Anyway,
once the hypoallergenic diet is chosen and feeding initiated, owners
must be very dedicated to not feeding anything BUT the diet. It takes
approximately 6-10 weeks for improvement to be seen. If improvement does
occur, then the dog can be fed its original diet to see if its allergic
condition returns to absolutely confirm that the food is the source of
the allergen. Then the dog is returned to the hypoallergenic diet and
kept on it for the rest of its life. Often, this is the only treatment
that is needed for food allergic dogs. Antihistamines and steroids are
typically ineffective in food allergy dogs. Typical age of onset is less
than 6 months and then greater than 6 years. Rarely are vomiting,
diarrhea, or other gastrointestinal upsets associated with food allergy.
Frustratingly, allergies are often a combination of these three types
especially food allergies and atopy. Diagnosing and treating these
combinations is difficult at best and impossible at times. Steroids have
long been the mainstay of allergy treatments, but as the veterinarian
community recognizes more and more the damage that long term steriods do
the more it tries to incorporate a multifactorial approach to treating
allergies so that the amount of steroids can be reduced to as low as
dose as possible if not eliminated altogether.
Diet -- even in atopic and flea allergic dogs diet can help reduce
signs. Diets high in Omega-3-fatty acids (like Eukanuba) can help reduce
allergic reactions. Homemade diets are becoming more and more popular
for allergic dogs and many dogs respond dramatically to a preservative
free, freshly made diet. The drawback to this is the time that it takes
to research how to properly make a homemade diet and the time to
actually make it.
Omega-3-fatty acids -- these fatty acids replace Omega-6 fatty acids in
the body and thereby lead to less chemicals produced that initiate
allergic signs. In fact, some of the chemicals Omega-3 fatty acids are
converted to reduce allergic signs. Fish oil and flaxseed oil are two
good sources of Omega-3 fatty acids.
Vitamin E, C, and A -- these are considered anti-oxidants and work by
reducing the effects that body chemicals have in producing allergic
signs. Acupuncture -- stimulation of certain acupuncture points will
help reduce the "overeaction" of the immune system Antihistamines --
while they do produce drowsiness in animals they are less harmful in the
long run than steroids. They work by inhibiting histamine which is one
of the main body chemicals in producing allergic signs.
Topical shampoos and conditioners -- these help soothe the skin and
treat it from the outside in. Oatmeal baths have long been known to
reduce itchiness. Some of the topical treatments contain antihistamines
and other drugs that help reduce redness and itchiness.
Herbs -- each dog needs to have an individual protocol formulated but
some herbs that help with allergies are Scutellaria, Tribulus, and
Capillaris.
Allergies can be very frustrating for the dog, the owner, and the
veterinarian to deal effectively with. Some dogs respond so well to
treatment that all signs resolve, others are brought to a manageable
level, and, unfortunately, others are never made comfortable. Since
there is some evidence that allergies in part are hereditary, breeders
should strongly consider not breeding allergic dogs (and bitches)
especially the ones that are severely allergic. Back to Pawsitive Advice
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